产品目录
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K101310P Anti-PCNA Polyclonal Antibody
- 品牌：Solarbio
- 产地：北京
- 货号：K101310P
- 价格： ￥询价
- 发布日期： 2020-03-10
- 更新日期： 2024-04-19
产品详请
| 抗体名 | Anti-PCNA Polyclonal Antibody |
| 是否单克隆 | 否 |
| 靶点 | PIM1 |
| 宿主 | Rabbit |
| 纯度 | % |
| 免疫原 | A synthetic peptide of human PCNA |
| 产地 | 北京 |
| 品牌 | Solarbio |
| 货号 | K101310P |
| 保存条件 | Store at -20°C. Avoid freeze / thaw cycles. |
| 应用范围 | WB |
| 规格 | 100ul |
| 适应物种 | Human Mouse Rat |
| 亚型 | IgG |
| 标识物 | ATLD2;cb16;Cyclin;HGCN872;MGC8367 |
| 浓度 | % |
| 是否进口 | 否 |
Anti-PCNA Polyclonal Antibody
品牌：solarbio | 货号：K101310P
| 商品货号： | 商品品牌： | 规格 | 基本售价： | 选择规格 |
|---|---|---|---|---|
| K101310P-50ul | solarbio | 50ul | 960.00元 | |
| K101310P-100ul | solarbio | 100ul | 1600.00元 |
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| 英文名称 | Anti-PCNA Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ATLD2;cb16;Cyclin;HGCN872;MGC8367 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 29kDa |
| Gene ID | 5111 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human PCNA |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human PCNA |
| Subcellular Locations | Nucleus |
| Swiss Prot | P12004 |
| *类型 | Polyclonal Antibody |
| 背景资料 | Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion. |
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