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人S100钙结合蛋白钙粒蛋白A Elisa试剂盒
起批量( 价格
≥1 ¥3200元/盒
  • 供货能力:999
  • 最低订购量:1盒
  • 可销售总数量:999盒
  • 建议零销价:3200元/盒
  • 发布日期: 2020-08-10
  • 更新日期: 2020-08-10
产品详细说明
品牌: Solarbio CAS编号:
产地: 北京 样本: 血清/血浆/细胞培养上清
标记物: 应用: Elisa试剂盒
检测方法: 双抗体夹心法 检测限: 31.2 - 2000 pg/mL
数量: 999 货号: SEKH-0421
纯度: % 用途范围: Human
规格: 是否进口:
保质期: 保存条件: -20
适应物种: Human
S100A8 (also MRP8 and calgranulin A) is a 10 kDa member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Human S100A8 is 93 amino acids (aa) in length. It contains two EF-hand motifs (aa 12 - 47 and 46 - 81) and one high-affinity Ca2+-binding site (aa 59 - 70). There may be one splice form that shows a 15 aa substitution for the C-terminal 14 amino acids. Although mouse S100A8 is cleaved by MMP-2 after Asn21, it is unclear if human S100A8 is susceptible. Full-length human S100A8 is 57% and 74% aa identical to mouse and canine S100A8, respectively.
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