产品目录
Anti-DUSP9 Polyclonal Antibody
物品单位 价格 品牌
1600 Solarbio
  • 产地:北京
  • 货号:K108249P
  • 发布日期: 2020-08-10
  • 更新日期: 2020-08-10
产品详细说明
CAS编号
抗体名 DUSP9
是否单克隆
靶点
用途范围 Human
形态
宿主
标记物
纯度 %
免疫原
产地 北京
品牌 Solarbio
货号 K108249P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 IHC
抗原来源
保质期
规格
产品用途 IHC
克隆性 Polyclonal Antibody
适应物种 Human
亚型 IgG
标识物
浓度 %
是否进口
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK; SAPK/JNK; p38); which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases; different tissue distribution and subcellular localization; and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.
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