| 英文名称 | Mouse HP1-γ Monoclonal Antibody |
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| 应用2 | WB IF IP IHC |
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| 克隆类型2 | Monoclonal Antibody |
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| 别名 | HP1-γ |
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| 应用 | WB,IF,IP,IHC |
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| 稀释比例 | WB1:1000 ICC1:200 |
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| 交叉反应 | Mouse Human Monkey Hamster Rat |
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| 蛋白分子量 | 22kDa |
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| Gene ID | 11335 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 64% Glycerol. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG1 |
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| 免疫原 | Purified recombinant human HP1-gamma protein fragments expressed in E.coli. |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | Q13185 |
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| 克隆号 | 5G10-F7-A12 |
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| 克隆类型 | Monoclonal Antibody |
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| 来源 | Mouse |
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| 背景资料 | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011] |
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