| 英文名称 | Mouse HP1-α Monoclonal Antibody |
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| 应用2 | WB ICC IHC |
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| 克隆类型2 | Monoclonal Antibody |
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| 别名 | HP1-α |
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| 应用 | WB,ICC,IHC |
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| 稀释比例 | WB1:1000 ICC1:300 |
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| 交叉反应 | Human Mouse |
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| 蛋白分子量 | 26kDa |
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| Gene ID | 23468 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 66% Glycerol. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG2b |
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| 免疫原 | Purified recombinant human HP1 alpha protein fragments expressed in E.coli. |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | P45973 |
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| 克隆号 | 3G2-H10-A6 |
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| 克隆类型 | Monoclonal Antibody |
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| 来源 | Mouse |
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| 背景资料 | This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
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