| 英文名称 | Rabbit CYP1A2 Polyclonal Antibody |
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| 应用2 | WB |
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| 克隆类型2 | Polyclonal Antibody |
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| 别名 | CP12;P3-450;P450(PA)
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| 应用 | WB |
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| 稀释比例 | WB1:500-1:2000 |
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| 交叉反应 | Mouse Rat |
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| 蛋白分子量 | 58kDa |
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| Gene ID | 1544 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | Recombinant Protein of human CYP1A2 |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | P05177 |
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| 克隆类型 | Polyclonal Antibody |
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| 来源 | Rabbit |
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| 背景资料 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. |
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