| 英文名称 | Rabbit PRF1 Polyclonal Antibody |
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| 应用2 | WB IHC IF |
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| 克隆类型2 | Polyclonal Antibody |
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| 别名 | FLH2;HPLH2;P1;PFN1;PFP
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| 应用 | WB,IHC,IF |
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| 稀释比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:200 |
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| 交叉反应 | Human Mouse |
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| 蛋白分子量 | 61kDa |
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| Gene ID | 5551 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | Recombinant protein of human PRF1 |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | P14222 |
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| 克隆类型 | Polyclonal Antibody |
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| 来源 | Rabbit |
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| 背景资料 | The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. |
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