| 英文名称 | Rabbit LRP5 Polyclonal Antibody |
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| 应用2 | WB IHC |
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| 克隆类型2 | Polyclonal Antibody |
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| 别名 | BMND1;EVR1;EVR4;HBM;LR3;LRP-5;LRP7;OPPG;OPS;OPTA1;VBCH2
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| 应用 | WB,IHC |
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| 稀释比例 | WB1:500-1:2000 IHC1:50-1:200 |
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| 交叉反应 | Human Mouse Rat |
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| 蛋白分子量 | 179kDa |
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| Gene ID | 4041 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | Recombinant protein of human LRP5 |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | O75197 |
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| 克隆类型 | Polyclonal Antibody |
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| 来源 | Rabbit |
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| 背景资料 | This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. |
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