英文名称 | Rabbit GDF15 Polyclonal Antibody |
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应用2 | WB IHC |
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克隆类型2 | Polyclonal Antibody |
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别名 | GDF-15;MIC-1;MIC1;NAG-1;PDF;PLAB;PTGFB
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应用 | WB,IHC |
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稀释比例 | WB1:500-1:2000 IHC1:50-1:200 |
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交叉反应 | Human Rat |
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蛋白分子量 | 34kDa |
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Gene ID | 9518 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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纯化方法 | Affinity purification |
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亚型 | IgG |
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免疫原 | Recombinant protein of human GDF15 |
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性状 | Lyophilized or Liquid |
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Swiss Prot | Q99988 |
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克隆类型 | Polyclonal Antibody |
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来源 | Rabbit |
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背景资料 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. |
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