| 英文名称 | Rabbit CASP10 Polyclonal Antibody |
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| 别名 | ALPS2;FLICE2;MCH4
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| 应用 | WB,IF |
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| 稀释比例 | WB1:500-1:2000 IF1:50-1:200 |
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| 交叉反应 | Human |
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| 蛋白分子量 | 59kDa |
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| Gene ID | 843 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | Recombinant protein of human CASP10 |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | Q92851 |
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| 克隆类型 | Polyclonal Antibody |
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| 来源 | Rabbit |
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| 背景资料 | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
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