英文名称 | Rabbit DDIT3 Polyclonal Antibody |
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应用2 | WB IHC IF |
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克隆类型2 | Polyclonal Antibody |
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别名 | CEBPZ;CHOP;CHOP-10;CHOP10;GADD153
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应用 | WB,IHC,IF |
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稀释比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:100 |
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交叉反应 | Human Mouse Rat |
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蛋白分子量 | 19kDa |
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Gene ID | 1649 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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纯化方法 | Affinity purification |
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亚型 | IgG |
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免疫原 | A synthetic peptide of human DDIT3 |
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性状 | Lyophilized or Liquid |
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Swiss Prot | P35638 |
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克隆类型 | Polyclonal Antibody |
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来源 | Rabbit |
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背景资料 | This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
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