英文名称 | Rabbit SIRT1 Polyclonal Antibody |
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应用2 | IHC |
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克隆类型2 | Polyclonal Antibody |
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别名 | SIR2;SIR2L1;SIR2alpha
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应用 | IHC |
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稀释比例 | IHC1:50-1:200 |
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交叉反应 | Human Mouse |
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蛋白分子量 | 82kDa |
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Gene ID | 23411 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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纯化方法 | Affinity purification |
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亚型 | IgG |
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免疫原 | A synthetic peptide of human SIRT1 |
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性状 | Lyophilized or Liquid |
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Swiss Prot | Q96EB6 |
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克隆类型 | Polyclonal Antibody |
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来源 | Rabbit |
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背景资料 | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. |
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