英文名称 | Rabbit IGF1R Polyclonal Antibody |
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应用2 | WB IHC |
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克隆类型2 | Polyclonal Antibody |
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别名 | CD221;IGFIR;IGFR;JTK13
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应用 | WB,IHC |
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稀释比例 | WB1:500-1:2000 IHC1:50-1:100 |
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交叉反应 | Human Mouse |
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蛋白分子量 | 155kDa |
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Gene ID | 3480 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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纯化方法 | Affinity purification |
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亚型 | IgG |
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免疫原 | A synthetic peptide of human IGF1R |
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性状 | Lyophilized or Liquid |
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Swiss Prot | P08069 |
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克隆类型 | Polyclonal Antibody |
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来源 | Rabbit |
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背景资料 | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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