| 英文名称 | Rabbit PRKCA Polyclonal Antibody |
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| 应用2 | WB IHC IF |
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| 克隆类型2 | Polyclonal Antibody |
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| 别名 | AAG6;PKC-alpha;PKCA;PRKACA
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| 应用 | WB,IHC,IF |
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| 稀释比例 | WB1:500-1:2000 IHC1:50-1:100 IF1:10-1:100 |
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| 交叉反应 | Human Mouse Rat |
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| 蛋白分子量 | 77kDa |
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| Gene ID | 5578 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | A synthetic peptide of human PRKCA |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | P17252 |
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| 克隆类型 | Polyclonal Antibody |
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| 来源 | Rabbit |
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| 背景资料 | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
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