| 英文名称 | Rabbit INSR Polyclonal Antibody |
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| 应用2 | WB IHC |
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| 克隆类型2 | Polyclonal Antibody |
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| 别名 | CD220;HHF5
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| 应用 | WB,IHC |
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| 稀释比例 | WB1:500-1:2000 IHC1:50-1:100 |
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| 交叉反应 | Human Mouse Rat |
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| 蛋白分子量 | 156kDa |
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| Gene ID | 3643 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | A synthetic peptide of human INSR |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | P06213 |
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| 克隆类型 | Polyclonal Antibody |
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| 来源 | Rabbit |
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| 背景资料 | This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. |
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