| 英文名称 | Rabbit CDKN1B Polyclonal Antibody |
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| 应用2 | WB IHC IF |
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| 克隆类型2 | Polyclonal Antibody |
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| 别名 | CDKN4;KIP1;MEN1B;MEN4;P27KIP1
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| 应用 | WB,IHC,IF |
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| 稀释比例 | WB1:200-1:500 IHC1:50-1:200 IF1:20-1:50 |
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| 交叉反应 | Human Mouse Rat |
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| 蛋白分子量 | 22kDa |
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| Gene ID | 1027 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | Recombinant protein of human CDKN1B |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | P46527 |
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| 克隆类型 | Polyclonal Antibody |
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| 来源 | Rabbit |
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| 背景资料 | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). |
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