| 英文名称 | Rabbit BCL2L11 Polyclonal Antibody |
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| 应用2 | WB IF |
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| 别名 | BAM;BIM;BOD
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| 应用 | WB,IF |
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| 稀释比例 | WB1:500-1:2000 IF1:100-1:200 |
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| 交叉反应 | Human Mouse Rat |
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| 蛋白分子量 | 22kDa |
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| Gene ID | 10018 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | Recombinant protein of human BCL2L11 |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | O43521 |
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| 克隆类型 | Polyclonal Antibody |
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| 来源 | Rabbit |
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| 背景资料 | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. |
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