| 英文名称 | Rabbit ESR1 Polyclonal Antibody |
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| 应用2 | WB |
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| 克隆类型2 | Polyclonal Antibody |
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| 别名 | ER;ESR;ESRA;ESTRR;Era;NR3A1
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| 应用 | WB |
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| 稀释比例 | WB1:1000-1:4000 |
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| 交叉反应 | Human Mouse |
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| 蛋白分子量 | 66kDa |
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| Gene ID | 2099 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | Recombinant protein of human ESR1 |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | P03372 |
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| 克隆类型 | Polyclonal Antibody |
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| 来源 | Rabbit |
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| 背景资料 | This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. |
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