产品目录
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Anti-NUP98 Polyclonal Antibody / 50μl
- 品牌：solarbio
- 产地：北京
- 货号：K001697P
- 价格： ￥询价
- 发布日期： 2018-07-13
- 更新日期： 2024-05-16
产品详请
| 产地 | 北京 |
| 品牌 | solarbio |
| 保存条件 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 货号 | K001697P |
| 应用范围 | WB |
| 抗体名 | Anti-NUP98 Polyclonal Antibody |
| 靶点 | 1支/50μl/960RMB |
| 适应物种 | Human Mouse |
| 形态 | Lyophilized or Liquid |
| 宿主 | Rabbit |
| 亚型 | IgG |
| 浓度 | % |
| 免疫原 | Recombinant protein of human NUP98 |
| 英文名称 | Rabbit NUP98 Polyclonal Antibody |
|---|---|
| 应用2 | WB |
| 克隆类型2 | Polyclonal Antibody |
| 别名 | ADIR2;NUP196;NUP96 |
| 应用 | WB |
| 稀释比例 | WB1:1000-1:2000 |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 198kDa |
| Gene ID | 4928 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NUP98 |
| 性状 | Lyophilized or Liquid |
| Swiss Prot | P52948 |
| 克隆类型 | Polyclonal Antibody |
| 来源 | Rabbit |
| 背景资料 | Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin. |
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