英文名称 | Rabbit NEDD4 Polyclonal Antibody |
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应用2 | WB IHC |
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克隆类型2 | Polyclonal Antibody |
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别名 | NEDD4-1;RPF1
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应用 | WB,IHC |
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稀释比例 | WB1:500-1:2000 IHC1:50-1:200 |
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交叉反应 | Human |
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蛋白分子量 | 149kDa |
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Gene ID | 4734 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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纯化方法 | Affinity purification |
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亚型 | IgG |
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免疫原 | Recombinant protein of human NEDD4 |
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性状 | Lyophilized or Liquid |
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Swiss Prot | P46934 |
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克隆类型 | Polyclonal Antibody |
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来源 | Rabbit |
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背景资料 | This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. |
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