产品目录
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Anti-DYRK1A Polyclonal Antibody / 100μl
- 品牌：solarbio
- 产地：北京
- 货号：K001710P
- 价格： ￥询价
- 发布日期： 2018-07-13
- 更新日期： 2024-04-29
产品详请
| 产地 | 北京 |
| 品牌 | solarbio |
| 保存条件 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 货号 | K001710P |
| 应用范围 | WB |
| 抗体名 | Anti-DYRK1A Polyclonal Antibody |
| 靶点 | 1支/100μl/1600RMB |
| 适应物种 | Human Mouse Rat |
| 形态 | Lyophilized or Liquid |
| 宿主 | Rabbit |
| 亚型 | IgG |
| 浓度 | % |
| 免疫原 | Recombinant protein of human DYRK1A |
| 英文名称 | Rabbit DYRK1A Polyclonal Antibody |
|---|---|
| 别名 | DYRK;DYRK1;HP86;MNB;MNBH;MRD7 |
| 应用 | WB |
| 稀释比例 | WB1:500-1:1000 |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 86kDa |
| Gene ID | 1859 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DYRK1A |
| 性状 | Lyophilized or Liquid |
| Swiss Prot | Q13627 |
| 克隆类型 | Polyclonal Antibody |
| 来源 | Rabbit |
| 背景资料 | This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. |
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