| 英文名称 | Rabbit TCL1A Polyclonal Antibody |
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| 应用2 | WB IHC IF |
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| 克隆类型2 | Polyclonal Antibody |
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| 别名 | TCL1
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| 应用 | WB,IHC,IF |
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| 稀释比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:10-1:100 |
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| 交叉反应 | Human Rat |
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| 蛋白分子量 | 13kDa |
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| Gene ID | 8115 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | Recombinant protein of human TCL1A |
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| 性状 | Lyophilized or Liquid |
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| Swiss Prot | P56279 |
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| 克隆类型 | Polyclonal Antibody |
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| 来源 | Rabbit |
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| 背景资料 | Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).
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