英文名称 | Anti-Casp9 Polyclonal Antibody |
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宿主 | Rabbit |
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别名 | CT30;DP4;HCA661;E2F like;Cancer/testis antigen 30 |
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应用 | WB |
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稀释比例 | WB 1:5000. |
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交叉反应 | Human |
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蛋白分子量 | 17/30/37/46kDa |
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Gene ID | 842 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles. |
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储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
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纯化方法 | Affinity purification |
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亚型 | IgG |
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免疫原 | Recombinant protein of human Casp9 |
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性状 | 液体 |
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Public Immunogen Range | Recombinant protein of human Casp9 |
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Swiss Prot | p55211 |
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Subcellular Locations | Cytosol Nucleus |
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*类型 | Polyclonal Antibody |
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背景资料 | Caspase 9, apoptosis-related cysteine protease (CASP9, synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Caspase 9 is processed by APAF1; this step is thought to be one of the earliest in the caspase activation cascade. 10380-1-AP can recognize the pre- and cleaved- caspase 9. |
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