Anti-NQO1 Polyclonal Antibody
- 发布日期: 2019-05-13
- 更新日期: 2025-05-13
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
货号 |
K106519P
|
应用范围 |
WB
|
CAS编号 |
|
抗体名 |
Anti-NQO1 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse Rat
|
形态 |
|
宿主 |
Rabbit
|
亚型 |
IgG
|
标识物 |
DHQU;DIA4;DTD;n MOR1;n MORI;QR1
|
浓度 |
%
|
免疫原 |
A synthetic peptide of human NQO1
|
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.