北京索莱宝科技有限公司
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Anti-ERK1/2 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K106589P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-08-08
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K106589P
应用范围 WB
CAS编号
抗体名 Anti-ERK1/2 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human Mouse Rat
形态
宿主 Rabbit
亚型 IgG
标识物 ERK;ERK-2;MAPK2;p38;p40;p41;p41mapk;p42-MAPK;P42MAPK;PRKM1;PRKM2
浓度 %
免疫原 Recombinant protein of human ERK1/2
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation.
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