Anti-KRT18 Polyclonal Antibody
- 发布日期: 2019-05-13
- 更新日期: 2025-08-08
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
货号 |
K106590P
|
应用范围 |
WB IHC
|
CAS编号 |
|
抗体名 |
Anti-KRT18 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse Rat
|
形态 |
|
宿主 |
Rabbit
|
亚型 |
IgG
|
标识物 |
CK-18;CYK18;K18;PIG46;Cytokeratin-18
|
浓度 |
%
|
免疫原 |
Recombinant protein of human KRT18
|
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.