北京索莱宝科技有限公司
产品展厅
Anti-KRT18 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K106590P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-08-08
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K106590P
应用范围 WB IHC
CAS编号
抗体名 Anti-KRT18 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human Mouse Rat
形态
宿主 Rabbit
亚型 IgG
标识物 CK-18;CYK18;K18;PIG46;Cytokeratin-18
浓度 %
免疫原 Recombinant protein of human KRT18
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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