北京索莱宝科技有限公司
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Anti-NR3C2 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K106612P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-05-13
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K106612P
应用范围 WB
CAS编号
抗体名 Anti-NR3C2 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human Mouse
形态
宿主 Rabbit
亚型 IgG
标识物 MCR;MLR;MR;NR3C2VIT
浓度 %
免疫原 A synthetic peptide of human NR3C2
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
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