Anti-NR3C2 Polyclonal Antibody
- 发布日期: 2019-05-13
- 更新日期: 2025-05-13
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
货号 |
K106612P
|
应用范围 |
WB
|
CAS编号 |
|
抗体名 |
Anti-NR3C2 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse
|
形态 |
|
宿主 |
Rabbit
|
亚型 |
IgG
|
标识物 |
MCR;MLR;MR;NR3C2VIT
|
浓度 |
%
|
免疫原 |
A synthetic peptide of human NR3C2
|
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.