北京索莱宝科技有限公司
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Anti-P27 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K106720P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-05-12
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K106720P
应用范围 IHC
CAS编号
抗体名 Anti-P27 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human
形态
宿主 Rabbit
亚型 IgG
标识物 CDKN1B;CDKN4;KIP1;MEN1B;MEN4;P27;KIP1;P27KIP1
浓度 %
免疫原 Recombinant protein of human P27
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4)
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