Anti-AKR1C3 Polyclonal Antibody
- 发布日期: 2019-05-13
- 更新日期: 2025-05-12
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
货号 |
K106744P
|
应用范围 |
WB
|
CAS编号 |
|
抗体名 |
Anti-AKR1C3 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human
|
形态 |
|
宿主 |
Rabbit
|
亚型 |
IgG
|
标识物 |
DDX;HAKRB;HSD17B5;KIAA0119;PGFS
|
浓度 |
%
|
免疫原 |
Recombinant protein of human AKR1C3
|
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.