北京索莱宝科技有限公司
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Anti-AKR1C3 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K106744P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-05-12
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K106744P
应用范围 WB
CAS编号
抗体名 Anti-AKR1C3 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human
形态
宿主 Rabbit
亚型 IgG
标识物 DDX;HAKRB;HSD17B5;KIAA0119;PGFS
浓度 %
免疫原 Recombinant protein of human AKR1C3
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.
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