Anti-GADD153 Polyclonal Antibody
- 发布日期: 2019-05-13
- 更新日期: 2025-05-12
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
货号 |
K106765P
|
应用范围 |
IHC
|
CAS编号 |
|
抗体名 |
Anti-GADD153 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human
|
形态 |
|
宿主 |
Rabbit
|
亚型 |
IgG
|
标识物 |
CEBPZ;CHOP;CHOP-10;CHOP10;GADD153;C/EBPzeta;DNA damage inducible transcript 3
|
浓度 |
%
|
免疫原 |
A synthetic peptide of human GADD153
|
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.