北京索莱宝科技有限公司
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Anti-GADD153 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K106765P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-05-12
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K106765P
应用范围 IHC
CAS编号
抗体名 Anti-GADD153 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human
形态
宿主 Rabbit
亚型 IgG
标识物 CEBPZ;CHOP;CHOP-10;CHOP10;GADD153;C/EBPzeta;DNA damage inducible transcript 3
浓度 %
免疫原 A synthetic peptide of human GADD153
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
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