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Anti-MCM10 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K106986P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-05-07
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K106986P
应用范围 WB IHC
CAS编号
抗体名 Anti-MCM10 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human
形态
宿主 Rabbit
亚型 IgG
标识物 CNA43;DNA43;HsMCM10;MCM10;PRO2249;Protein MCM10 homolog
浓度 %
免疫原 Recombinant protein of human MCM10
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified
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