北京索莱宝科技有限公司
产品展厅
Anti-OAS1 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K107025P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-05-06
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K107025P
应用范围 IHC
CAS编号
抗体名 Anti-OAS1 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human
形态
宿主 Rabbit
亚型 IgG
标识物 E18/E16;IFI-4;OIAS;OIASI;2'-5'-oligoadenylate synthase 1
浓度 %
免疫原 A synthetic peptide of human OAS1
This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.
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