Anti-LMP7 Polyclonal Antibody
- 发布日期: 2019-05-13
- 更新日期: 2025-05-06
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
货号 |
K107052P
|
应用范围 |
IHC
|
CAS编号 |
|
抗体名 |
Anti-LMP7 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse Rat
|
形态 |
|
宿主 |
Rabbit
|
亚型 |
IgG
|
标识物 |
PSMB9;LMP2;PSMB6i;RING12;beta1i;proteasome subunit beta 9
|
浓度 |
%
|
免疫原 |
A synthetic peptide of human LMP7
|
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.