北京索莱宝科技有限公司
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Anti-CD35 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K107138P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-08-05
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K107138P
应用范围 IHC
CAS编号
抗体名 Anti-CD35 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human
形态
宿主 Rabbit
亚型 IgG
标识物 C3BR;C4BR;CD35;KN;complement receptor type 1
浓度 %
免疫原 A synthetic peptide of human CD35
This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized.
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