Anti-CD35 Polyclonal Antibody
                            
                                
                                    
                                    
                                    
                                    
                                        - 发布日期: 2019-05-13
 
                                        - 更新日期: 2025-11-04
 
                                    
                                 
                             
                            
                         
                        
                     
                    
                 
             
            产品详请
            
                
                    
                    
                        | 产地  | 
                        
                            北京
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                        | 品牌  | 
                        
                            Solarbio
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                        | 保存条件  | 
                        
                            Store at -20°C. Avoid freeze / thaw cycles.
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                        | 货号  | 
                        
                            K107138P
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                        | 应用范围  | 
                        
                            IHC
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                        | CAS编号  | 
                        
                            
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                        | 抗体名  | 
                        
                            Anti-CD35 Polyclonal Antibody
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                        | 克隆性  | 
                        
                            Polyclonal Antibody
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                        | 靶点  | 
                        
                            
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                        | 适应物种  | 
                        
                            Human
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                        | 形态  | 
                        
                            
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                        | 宿主  | 
                        
                            Rabbit
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                        | 亚型  | 
                        
                            IgG
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                        | 标识物  | 
                        
                            C3BR;C4BR;CD35;KN;complement receptor type 1
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                        | 浓度  | 
                        
                            %
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                        | 免疫原  | 
                        
                            A synthetic peptide of human CD35
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                This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized.