北京索莱宝科技有限公司
产品展厅
Anti-INSR Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K106883P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-05-06
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K106883P
应用范围 WB
CAS编号
抗体名 Anti-INSR Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human
形态
宿主 Rabbit
亚型 IgG
标识物 CD220;HHF5;insulin receptor
浓度 %
免疫原 A synthetic peptide of human INSR
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
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