北京索莱宝科技有限公司
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Anti-Claudin 8 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K106884P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-05-06
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K106884P
应用范围 IHC
CAS编号
抗体名 Anti-Claudin 8 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human
形态
宿主 Rabbit
亚型 IgG
标识物 CLDN8;HEL-S-79
浓度 %
免疫原 A synthetic peptide of human Claudin 8
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.
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