北京索莱宝科技有限公司
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Anti-IDH3B Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K107071P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-05-06
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K107071P
应用范围 WB IHC
CAS编号
抗体名 Anti-IDH3B Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human Mouse
形态
宿主 Rabbit
亚型 IgG
标识物 RP46
浓度 %
免疫原 Recombinant protein of human IDH3B
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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