Anti-IDH3B Polyclonal Antibody
- 发布日期: 2019-05-13
- 更新日期: 2025-10-31
产品详请
| 产地 |
北京
|
| 品牌 |
Solarbio
|
| 保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 货号 |
K107071P
|
| 应用范围 |
WB IHC
|
| CAS编号 |
|
| 抗体名 |
Anti-IDH3B Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶点 |
|
| 适应物种 |
Human Mouse
|
| 形态 |
|
| 宿主 |
Rabbit
|
| 亚型 |
IgG
|
| 标识物 |
RP46
|
| 浓度 |
%
|
| 免疫原 |
Recombinant protein of human IDH3B
|
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.