Anti-IDH3B Polyclonal Antibody
- 发布日期: 2019-05-13
- 更新日期: 2025-05-06
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
货号 |
K107071P
|
应用范围 |
WB IHC
|
CAS编号 |
|
抗体名 |
Anti-IDH3B Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse
|
形态 |
|
宿主 |
Rabbit
|
亚型 |
IgG
|
标识物 |
RP46
|
浓度 |
%
|
免疫原 |
Recombinant protein of human IDH3B
|
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.