Anti-TFPI Polyclonal Antibody
- 价格: ¥询价
- 发布日期: 2019-05-13
- 更新日期: 2024-05-17
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
货号 |
K107098P
|
应用范围 |
WB IHC
|
抗体名 |
Anti-TFPI Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
适应物种 |
Human Mouse Rat
|
宿主 |
Rabbit
|
亚型 |
IgG
|
标识物 |
EPI;Extrinsic pathway inhibitor;LACI;TFI;TFPI;TFPI1
|
浓度 |
%
|
免疫原 |
Recombinant protein of human TFPI
|
This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization.?