Anti-RNF146 Polyclonal Antibody
- 价格: ¥询价
- 发布日期: 2019-05-13
- 更新日期: 2024-05-17
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
货号 |
K107102P
|
应用范围 |
IHC
|
抗体名 |
Anti-RNF146 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
适应物种 |
Human
|
宿主 |
Rabbit
|
亚型 |
IgG
|
标识物 |
dactylidin;dJ351K20.1;DKFZp434O1427
|
浓度 |
%
|
免疫原 |
Recombinant protein of human RNF146
|
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF146 (RING finger protein 146), also known as Dactylidin, is a 359 amino acid protein that contains one RING-type zinc finger and one WWE domain. Via its RING-type zinc finger, RNF146 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF146 are associated with Alzheimer's disease (AD) and may lead to a higher risk of breast cancer. Two isoforms of RNF146 exist due to alternative splicing events.