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Anti-ALDOB Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K107157P
  • 发布日期: 2019-05-13
  • 更新日期: 2025-08-01
产品详请
产地 北京
品牌 Solarbio
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
货号 K107157P
应用范围 WB IHC
CAS编号
抗体名 Anti-ALDOB Polyclonal Antibody
克隆性 Polyclonal Antibody
靶点
适应物种 Human Mouse Rat Cow Shp Rb
形态
宿主 Rabbit
亚型 IgG
标识物 ALDB;ALDO2;fructose-bisphosphate aldolase B
浓度 %
免疫原 A synthetic peptide of human ALDOB
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
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