英文名称 Anti-Lamin B1 Monoclonal Antibody

宿主 Mouse

别名 ADLD; LMB1;LMNB1; MGC111419; OTTHUMP00000159218

应用 WB IP

稀释比例 WB 1:2000-5000. IP 1:100-300.

交叉反应 Human Mouse Rat

蛋白分子量 68kDa

Gene ID 4001

保存 Store at -20°C. Avoid freeze / thaw cycles.

储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

纯化方法 Affinity purification

亚型 IgG1

免疫原 A synthetic peptide coupled to KLH

性状 液体

Public Immunogen Range A synthetic peptide coupled to KLH

Subcellular Locations Nucleus

Swiss Prot P20700

*号 7C11

*类型 Monoclonal Antibody

背景资料 The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

参考文献

《Lactobacillus plantarum NA136 improves the non-alcoholic fatty liver disease by modulating the AMPK/Nrf2 pathway》 作者:Zijian Zhao,Chao Wang,Li Zhang,Yujuan Zhao,Cuicui Duan,Xue Zhang ,Lei Gao,Shengyu Li 期刊:Applied Microbiology and Biotechnology 影响因子:3.67 PMID:31115630