Anti-PPP3CA Polyclonal Antibody
- 发布日期： 2020-03-03
- 更新日期： 2026-01-22
产品详请
| 产地 |
北京
|
| 品牌 |
Solarbio
|
| 货号 |
K107562P
|
| 保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 用途 |
蛋白研究，分析，检测
|
| 应用范围 |
IHC
|
| 抗原来源 |
|
| CAS编号 |
|
| 保质期 |
|
| 抗体名 |
CALN; CALNA; CALNA1; CCN1; CNA1; PPP2B; protein phosphatase 3 catalytic subunit alpha
|
| 是否单克隆 |
否
|
| 克隆性 |
Polyclonal Antibody
|
| 靶点 |
PPP3CA
|
| 适应物种 |
Human Mouse Rat Cow
|
| 形态 |
液体
|
| 宿主 |
Rabbit
|
| 标记物 |
|
| 包装规格 |
50ul
|
| 纯度 |
%
|
| 亚型 |
IgG
|
| 标识物 |
|
| 浓度 |
%
|
| 免疫原 |
A synthetic peptide of human PPP3CA
|
| 是否进口 |
否
|
Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca2+-mediated signals (PubMed:15671020, PubMed:18838687, PubMed:19154138, PubMed:23468591). Many of the substrates contain a PxIxIT motif and/or a LxVP motif (PubMed:17498738, PubMed:17502104, PubMed:23468591, PubMed:27974827, PubMed:22343722). In response to increased Ca2+?levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation (PubMed:15671020). In response to increased Ca2+?levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion (PubMed:18838687). Dephosphorylates heat shock protein HSPB1 (By similarity). Dephosphorylates and activates transcription factor NFATC1 (PubMed:19154138). In response to increased Ca2+?levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation (PubMed:26248042). Dephosphorylates and inactivates transcription factor ELK1 (PubMed:19154138). Dephosphorylates DARPP32 (PubMed:19154138).
