北京索莱宝科技有限公司
产品展厅
Anti-CDKAP1 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K107629P
  • 发布日期: 2020-03-03
  • 更新日期: 2026-01-22
产品详请
产地 北京
品牌 Solarbio
货号 K107629P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
用途 蛋白研究,分析,检测
应用范围 WB IHC
抗原来源
CAS编号
保质期
抗体名 DOC1; DORC1; ST19; doc-1; p12DOC-1; cyclin-dependent kinase 2-associated protein 1
是否单克隆
克隆性 Polyclonal Antibody
靶点 CDKAP1
适应物种 Human Mouse
形态 液体
宿主 Rabbit
标记物
包装规格 50ul
纯度 %
亚型 IgG
标识物
浓度 %
免疫原 A synthetic peptide of human CDKAP1
是否进口
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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