Anti-TNFSF8 Polyclonal Antibody
- 发布日期: 2020-03-03
- 更新日期: 2026-01-22
产品详请
| 产地 |
北京
|
| 品牌 |
Solarbio
|
| 货号 |
K107638P
|
| 保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 用途 |
蛋白研究,分析,检测
|
| 应用范围 |
WB
|
| 抗原来源 |
|
| CAS编号 |
|
| 保质期 |
|
| 抗体名 |
CD153; CD30L; CD30LG; TNLG3A; TNF superfamily member 8
|
| 是否单克隆 |
否
|
| 克隆性 |
Polyclonal Antibody
|
| 靶点 |
TNFSF8
|
| 适应物种 |
Human Mouse
|
| 形态 |
液体
|
| 宿主 |
Rabbit
|
| 标记物 |
|
| 包装规格 |
50ul
|
| 纯度 |
%
|
| 亚型 |
IgG
|
| 标识物 |
|
| 浓度 |
%
|
| 免疫原 |
A synthetic peptide of human TNFSF8
|
| 是否进口 |
否
|
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.