背景资料：MMGT1 (membrane magnesium transporter 1), also known as TMEM32 (transmembrane protein 32), is a 131 amino acid single-pass type I membrane protein of the endoplasmic reticulum, golgi apparatus and early endosome that belongs to the membrane magnesium transporter family. As such, MMGT1 mediates magnesium transport and exists as two alternatively spliced isoforms. The gene encoding MMGT1 maps to human chromosome Xq26.3. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of a X and Y chromosome lead to normal male development while two copies of X lead to normal female development.