背景资料：Solute carrier family 7 member 5 also known as large neutral amino acids transporter small subunit 1 is a protein that in humans is encoded by the SLC7A5gene. LAT1 is expressed predominantly in adult lung and liver but is also expressed in brain, thymus, retina, testis, placenta, bone marrow and fetal liver. In the retina, LAT1 localizes to the blood-retinal-barrier (BRB) and mediates L-leucine transport from the blood to the retina.