K009382PAnti-IL10 Polyclonal Antibody
- 价格: ¥960/支
- 发布日期: 2020-03-04
- 更新日期: 2023-09-28
产品详请
抗体名 |
Anti-IL10 Polyclonal Antibody
|
是否单克隆 |
否
|
靶点 |
IL10
|
用途范围 |
WB 1:500-2000. IHC 1:50-100.
|
形态 |
液体
|
宿主 |
Rabbit
|
纯度 |
%
|
免疫原 |
Recombinant protein of human IL10
|
产地 |
北京
|
品牌 |
solarbio
|
货号 |
K009382P
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
应用范围 |
WB IHC
|
规格 |
50ul
|
产品用途 |
蛋白研究,分析,检测
|
适应物种 |
Human Mouse Rat
|
亚型 |
IgG
|
浓度 |
%
|
是否进口 |
否
|
背景资料:The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.