产品目录
Anti-COPS7B Polyclonal Antibody
物品单位 价格 品牌
1600 Solarbio
  • 产地:北京
  • 货号:K108031P
  • 发布日期: 2020-08-10
  • 更新日期: 2020-08-10
产品详细说明
CAS编号
抗体名 COPS7B
是否单克隆
靶点
用途范围 Human
形态
宿主 Rabbit
标记物
纯度 %
免疫原
产地 北京
品牌 Solarbio
货号 K108031P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB IHC
抗原来源
保质期
规格
产品用途 WB IHC
克隆性 Polyclonal Antibody
适应物种 Human
亚型 IgG
标识物
浓度 %
是否进口
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
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