Anti-ISCU Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K108041P
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-07-19
产品详请
产地 北京
品牌 Solarbio
货号 K108041P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
用途 IHC
应用范围 IHC
抗体名 ISCU
是否单克隆
克隆性 Polyclonal Antibody
适应物种 Human
宿主 Rabbit
纯度 %
亚型 IgG
浓度 %
是否进口
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
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