Anti-RYBP Polyclonal Antibody
- 发布日期: 2020-08-10
- 更新日期: 2024-11-06
产品详请
产地 |
北京
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品牌 |
Solarbio
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货号 |
K108142P
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保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
用途 |
WB IHC
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应用范围 |
WB IHC
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抗原来源 |
|
CAS编号 |
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保质期 |
|
抗体名 |
RYBP
|
是否单克隆 |
否
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse Rat
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形态 |
|
宿主 |
Rabbit
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标记物 |
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包装规格 |
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纯度 |
%
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亚型 |
IgG
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标识物 |
|
浓度 |
%
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免疫原 |
|
是否进口 |
否
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Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1-like complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Component of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females. May stimulate ubiquitination of histone H2A 'Lys-119' by recruiting the complex to target sites (By similarity). Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May also regulate the ubiquitin-mediated proteasomal degradation of other proteins like FANK1 to regulate apoptosis. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA (By similarity). May play a role in the repression of tumor growth and metastasis in breast cancer by down-regulating SRRM3 .