Anti-RYBP Polyclonal Antibody
                            
                                
                                    
                                    
                                    
                                    
                                        - 发布日期: 2020-08-10
- 更新日期: 2025-10-31
 
                             
                            
                         
                        
                     
                    
                 
             
            产品详请
            
                
                    
                    
                        | 产地 | 北京 | 
                    
                        | 品牌 | Solarbio | 
                    
                        | 货号 | K108142P | 
                    
                        | 保存条件 | Store at -20°C. Avoid freeze / thaw cycles. | 
                    
                        | 用途 | WB IHC | 
                    
                        | 应用范围 | WB IHC | 
                    
                        | 抗原来源 |  | 
                    
                        | CAS编号 |  | 
                    
                        | 保质期 |  | 
                    
                        | 抗体名 | RYBP | 
                    
                        | 是否单克隆 | 否 | 
                    
                        | 克隆性 | Polyclonal Antibody | 
                    
                        | 靶点 |  | 
                    
                        | 适应物种 | Human Mouse Rat | 
                    
                        | 形态 |  | 
                    
                        | 宿主 | Rabbit | 
                    
                        | 标记物 |  | 
                    
                        | 包装规格 |  | 
                    
                        | 纯度 | % | 
                    
                        | 亚型 | IgG | 
                    
                        | 标识物 |  | 
                    
                        | 浓度 | % | 
                    
                        | 免疫原 |  | 
                    
                        | 是否进口 | 否 | 
                    
                
             
            
                Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1-like complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Component of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females. May stimulate ubiquitination of histone H2A 'Lys-119' by recruiting the complex to target sites (By similarity). Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May also regulate the ubiquitin-mediated proteasomal degradation of other proteins like FANK1 to regulate apoptosis. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA (By similarity). May play a role in the repression of tumor growth and metastasis in breast cancer by down-regulating SRRM3 .